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How many vials of Dantrolene are recommended to be kept readily available for treating malignant hyperthermia?

  1. 12

  2. 24

  3. 36

  4. 48

The correct answer is: 36

The recommendation for the number of vials of Dantrolene to have readily available for treating malignant hyperthermia is based on established guidelines and protocols. Malignant hyperthermia is a critical and potentially life-threatening condition that can occur during or after anesthesia, particularly with certain anesthetic agents. Dantrolene is the specific antidote used to manage this condition by reducing calcium release in the muscles, thereby correcting the hypermetabolic state. Having 36 vials of Dantrolene on hand ensures that sufficient doses are available to effectively manage cases of malignant hyperthermia. Each vial contains a specific dosage, and the dosing protocol often requires multiple vials to be administered rapidly in a life-threatening situation to achieve the desired therapeutic effect. This readiness is crucial because the onset of malignant hyperthermia can be rapid, necessitating immediate treatment to prevent severe complications or mortality. The other quantities are lower than the recommended guidelines, indicating that they may not provide an adequate stockpile to handle multiple cases or to ensure that enough medication is available in emergencies where rapid administration is critical. Therefore, having 36 vials prepares healthcare providers for effective and rapid intervention in the event of malignant hyperthermia, aligning with best practices in anesthetic safety.